Instrumentation

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BIACORE T100
Analysis of macromolecular interactions and binding kinetics
Instrument handbook | Software handbook | Concentration handbook | Sensor surface handbook | Assay handbook | Book time
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OctetForteBio Octet RED96
Analysis of macromolecular interactions and binding kinetics
Data acquisition manual | Data analysis manual | Sample preparation | SOP | Book time
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BIACORE 2000
This instrument is also available in the core facility
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Microcal iTC200
Isothermal titration calorimeter for minimal solution volumes
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Microcal VP-ITC
Isothermal titration calorimeter suitable for larger sample volumes
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Beckman Optima XL-I
Analytical ultracentrifuge with UV and interference optics
(the user manual is located next to the instrument)
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Aviv Model 410
Circular dichroism spectrometer with temperature control
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Cary 100 Scan
Spectrophotometer with temperature control for measurements of UV melting profiles
Sample preparation | SOP | Manual | Book time
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CFX
Bio-Rad CFX Connect
Real-time PCR detection system with 96-well reaction module, also suitable for differential scanning fluorimetry/thermal-shift assays
Sample preparation | SOP | General_manual plus addendum | Book time
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Malvern Zetasizer Nano S
Dynamic light scattering instrument to measure molecular size, from 0.3nm – 10µm/980Da – 2×107 Da
NB: zeta potential measurements are not possible with this model
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Affiliated instruments in Structural Biology include NMR spectrometers, X-ray diffractometers and nanodroplet crystallisation robots; the NMR Facility and Crystallographic X-ray Facility are located elsewhere in the Sanger building.